Doppiatori Italiani

Solid Snake: Alessandro Ricci
Meryl Silverburgh: Ilaria D'Elia
Liquid Snake: Andrea Piovan
Revolver Ocelot: Giancarlo Ciccone
Vulcan Raven: Giancarlo Ciccone
Sniper Wolf: Luciana Izzi
Psycho Mantis: Ciro Carraro
Roy Campbell: Angelo Cola
Naomi Hunter: Jessica Juffré
Mei Ling: Laura Farina
Nastasha Romanenko: Benedetta Ferraro
Hal Emmerich: Massimo Marinoni
Kenneth Baker: Luigi Chiappini
Donald Anderson: Andrea Piovan
Cyborg Ninja: Massimo Marinoni
Master Miller: Andrea Piovan
Jim Houseman: Luigi Chiappini
Johnny Sasaki: Luigi Chiappini
Soldati Genetici: Luigi Chiappini, Giancarlo Ciccone

Doppiatori Inglesi

Solid Snake: David Hayter
Meryl Silverburgh: Debi Mae West
Liquid Snake: Cam Clarke
Revolver Ocelot: Patrick Zimmerman
Vulcan Raven: Peter Lurie
Sniper Wolf: Tasia Valenza
Psycho Mantis: Doug Stone
Roy Campbell: Paul Eiding
Naomi Hunter: Jennifer Hale
Mei Ling: Kim Mai Guest
Nastasha Romanenko: Renee Raudman
Hal Emmerich: Cristopher Randolph
Kenneth Baker: Allan Lurie
Donald Anderson: Greg Eagles
Cyborg Ninja: Greg Eagles
Master Miller: Cam Clarke
Jim Houseman: William Bassett
Johnny Sasaki: Dean Scofield
Soldati Genetici: Dean Scofield, Scott Dolph